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The normal structure of the centromere, adapted from He D and Brinkley BR (1997). CENP-B is particularly positioned at the center domain of the kinetochore domain of a centromere. It has a DNA binding domain (DBD) in the N-terminal one hundred twenty five

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Figure 3. INMAP knockdown encourages N-terminal cleavage of CENP-B and CENP-BCT localizes out of...