Product Name: CTLA-4 (D4E9I) Rabbit mAb#15119
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1254473-64-7
Product: LY2874455
Specificity Sensitivity: CTLA-4 (D4E9I) Rabbit mAb recognizes endogenous levels of total CTLA-4 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp100 of human CTLA-4 protein.
Background: Cytotoxic T-lymphocyte protein 4 (CTLA-4, CD152) is an Ig superfamily member that negatively regulates early T cell activation (1-4). The CTLA-4 protein is primarily expressed on T cells, including CD8+ cytotoxic T cells, CD4+ helper T cells, and CD4+/Fox
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23702728?dopt=Abstract
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