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Product Name: Phospho-Zap-70 (Tyr493)/Syk (Tyr526) Antibody#2704
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 79517-01-4
Product: Octreotide (acetate)
Specificity Sensitivity: Phospho-Zap-70 (Tyr493)/Syk (Tyr526) Antibody detects endogenous levels of Zap-70 only when phosphorylated at Tyr493. This antibody may cross-react with other activated tyrosine kinases.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr493 of human Zap-70. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on severa
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21454556?dopt=Abstract

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Author: Interleukin Related