Product Name: Phospho-YAP (Ser127) Antibody#4911
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1333377-65-3
Product: CHR-6494
Specificity Sensitivity: Phospho-YAP (Ser127) Antibody detects endogenous levels of YAP only when phosphorylated at serine 127. This antibody may cross-react with phospho-TAZ (Ser89).
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP. Antibodies are purified by protein A and peptide affinity chromatography.
Background: YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. It also binds to other SH3 domain-containing proteins such as Nck, Crk, Src, and Abl (1). In addition to the SH3 binding motif, YAP contains a
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24845618?dopt=Abstract
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