Product Name: Vav2 (C64H2) Rabbit mAb#2848
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 301836-43-1
Product: D4476
Specificity Sensitivity: Vav2 (C64H2) Rabbit mAb detects endogenous levels of total Vav2 protein. The antibody is not expected to cross-react with Vav1 or Vav3 based on the sequence of the immunogenic peptide.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Vav2.
Background: Vav proteins belong to the Dbl family of guanine nucleotide exchange factors (GEFs) for Rho/Rac small GTPases. The three identified mammalian Vav proteins (Vav1, Vav2 and Vav3) differ in their expression. Vav1 is expressed only in hematopoietic cells and
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19066283?dopt=Abstract
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