Product Name: Upf2 (D3B10) Rabbit mAb#11875
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1431697-96-9
Product: CCT241533 (hydrochloride)
Specificity Sensitivity: Upf2 (D3B10) Rabbit mAb recognizes endogenous levels of total Upf2 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu391 of human Upf2 protein.
Background: Upf1 was identified as an active component in nonsense-mediated decay (NMD), an mRNA surveillance mechanism in eukaryotic cells that degrades mRNAs containing premature termination codons (1). Upf1 was found to be an ATP-dependent RNA helicase in the cyto
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20517466?dopt=Abstract
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