Product Name: Phospho-IRS-1 (Ser612) (L7B8) Mouse mAb#3193
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 156-54-7
Product: Sodium Butyrate
Specificity Sensitivity: Phospho-IRS-1 (Ser612) (L7B8) Mouse mAb detects endogenous IRS-1 only when phosphorylated at serine 612.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser612 of mouse IRS-1.
Background: Insulin receptor substrate 1 (IRS-1) is one of the major substrates of the insulin receptor kinase (1). IRS-1 contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain containing proteins that mediate the metabolic and g
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19959400?dopt=Abstract
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