Product Name: Phospho-IRS-1 (Ser307) Antibody#2381
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 57644-54-9
Product: Gastrodenol
Specificity Sensitivity: Phospho-IRS-1 (Ser307) Antibody detects endogenous IRS-1 only when phosphorylated at serine 307. This antibody does not cross-react with other related phospho-proteins.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser307 of mouse IRS-1 (equivalent to Ser312 of human IRS-1). Antibodies are purified by protein A and peptide affinity chromatog
Background: Insulin receptor substrate 1 (IRS-1) is one of the major substrates of the insulin receptor kinase (1). IRS-1 contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain containing proteins that mediate the metabolic and g
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24021630?dopt=Abstract
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