Product Name: IRG1 (D6H2Y) Rabbit mAb#77510
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1454846-35-5
Product: PF-06463922
Specificity Sensitivity: IRG1 (D6H2Y) Rabbit mAb recognizes endogenous levels of total IRG1 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly460 of human IRG1 protein.
Background: IRG1 (Immune-responsive gene 1) is one of the most up-regulated genes in macrophages under proinflammatory conditions (1). It is also highly expressed in the pregnant uterus during implantation (2,3). IRG1 is a cis-aconitate decarboxylase that produces it
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24966277?dopt=Abstract
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