Product Name: CDK7 (MO1) Mouse mAb#2916
Application: Dilutions
Western Blotting: 1:2000
Immunoprecipitation: 1:200
Immunohistochemistry: 1:1000
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 928659-70-5
Product: Eliglustat (hemitartrate)
Specificity Sensitivity: CDK7 (MO1) Mouse mAb detects endogenous levels of total CDK7 protein. The antibody does not cross-react with other CDKs.
Species Reactivity: Human, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with recombinant human CDK7.
Background: CDK-activating kinase (CAK) is a complex of CDK7 and cyclin H. The complex is involved in cell cycle regulation by phosphorylating an activating residue in the T-loop domain of cdks (1). Regulation of CAK activity is mediated by T-loop phosphorylation and
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/14507843?dopt=Abstract
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