Product Name: CDK4 (D9G3E) Rabbit mAb#12790
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:800
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1197194-61-8
Product: Endoxifen (E-isomer hydrochloride)
Specificity Sensitivity: CDK4 (D9G3E) Rabbit mAb recognizes endogenous levels of total CDK4 protein. In COS-7 cells, this antibody recognizes a 40 kDa background band of unknown origin. This antibody does not cross-react with CDK1, 2, or 6.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CDK4 protein.
Background: Cyclin-dependent kinase activity is regulated by T-loop phosphorylation (Thr172 in the case of CDK4), by the abundance of their cyclin partners, and by association with CDK inhibitors of the Cip/Kip or INK family of proteins (1). The inactive ternary comp
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15677564?dopt=Abstract
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