Product Name: CDIP Antibody#13824
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 393514-24-4
Product: BCTC
Specificity Sensitivity: CDIP Antibody recognizes endogenous levels of total CDIP protein. This antibody may detect proteins of unknown origin at 35 and 70 kDa in some cell lines.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human CDIP protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Cell Death Involved p53-Target (CDIP) is a pro-apoptotic protein induced by genotoxic stress in a p53-dependent manner (1). Indeed, CDIP is a direct target of p53. Inhibition of CDIP impairs p53-mediated apoptosis. Induction of apoptosis by CDIP requires
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17496059?dopt=Abstract
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