Product Name: Caspase-7 (D2Q3L) Rabbit mAb#12827
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1346547-00-9
Product: GSK583
Specificity Sensitivity: Caspase-7 (D2Q3L) Rabbit mAb recognizes endogenous levels of total caspase-7 protein. This antibody detects both the full-length (35 kDa) and large (20 kDa) subunits following caspase-7 activation.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro158 of human caspase-7 protein.
Background: Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis (1-4). Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as (ADP-ribose) polymerase and
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24048575?dopt=Abstract
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