Product Name: BCAT1 Antibody#12822
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1210608-43-7
Product: PIM447
Specificity Sensitivity: BCAT1 Antibody recognizes endogenous levels of total BCAT1 protein. This antibody cross-reacts with BCAT2.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human BCAT1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: BCAT1 and BCAT2 are cytosolic and mitochondrial branched chain aminotransferases, respectively (1,2). Research studies have implicated BCAT1 in distant metastasis in patients with advanced colorectal cancer (3). Disruption of BCAT2 in mice leads to higher
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9472036?dopt=Abstract
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