Product Name: Bak Antibody#3814
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 150145-89-4
Product: (S)-MCPG
Specificity Sensitivity: Bak Antibody detects endogenous levels of Bak protein. No cross reactivity was detected with other Bcl-2 family members.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly82 of human Bak. Antibodies were purified by protein A and peptide affinity chromatography.
Background: Bak is a proapoptotic member of the Bcl-2 family (1). This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway (2,3). Upon apoptotic stimulation, an
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23831688?dopt=Abstract
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