Product Name: Phospho-ATM (Ser1981) (D25E5) Rabbit mAb#13050
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 61477-94-9
Product: Pirmenol (hydrochloride)
Specificity Sensitivity: Phospho-ATM (Ser1981) (D25E5) Rabbit mAb recognizes endogenous levels of ATM protein only when phosphorylated at Ser1981.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser1981 of human ATM protein.
Background: Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair (1). Activation of ATM by autophosphorylation on Ser1981 occurs in response to exposed DNA double stranded breaks. ATM kinase regu
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19464311?dopt=Abstract
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