Product Name: ALK (31F12) Mouse mAb#3791
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1265965-22-7
Product: S49076
Specificity Sensitivity: ALK (31F12) Mouse mAb detects endogenous levels of total ALK protein. It does not cross-react with other related proteins.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant protein containing a fragment near the carboxy terminus of human ALK.
Background: Anaplastic lymphoma kinase (ALK) is a tyrosine kinase receptor for pleiotrophin (PTN), a growth factor involved in embryonic brain development (1-3). In ALK-expressing cells, PTN induces phosphorylation of both ALK and the downstream effectors IRS-1, Shc,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24599476?dopt=Abstract
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