Product Name: Phospho-ALK (Tyr1096) (D96H9) Rabbit mAb#6962
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1627696-51-8
Product: LY3177833
Specificity Sensitivity: Phospho-ALK (Tyr1096) (D96H10) Rabbit mAb detects ALK only when phosphorylated at Tyr1096 (equivalent to Tyr156 of NPM-ALK).
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1096 of human ALK protein.
Background: Anaplastic lymphoma kinase (ALK) is a tyrosine kinase receptor for pleiotrophin (PTN), a growth factor involved in embryonic brain development (1-3). In ALK-expressing cells, PTN induces phosphorylation of both ALK and the downstream effectors IRS-1, Shc,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26750705?dopt=Abstract
Interleukin Related interleukin-related.com
Just another WordPress site
