Product Name: ADAM10 Antibody#14194
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1392116-14-1
Product: JD-5037
Specificity Sensitivity: ADAM10 Antibody recognizes endogenous levels of total ADAM10 protein, including the active, mature 68 kDa protein and the 90 kDa precursor chain. The antibody also recognizes a 35 kDa protein of unknown origin.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ADAM10 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Members of the ADAM (a disintegrin and a metalloprotease) family of multidomain membrane proteins influence cell signaling and adhesion by shedding cell surface proteins, such as cytokines and growth factors. This process influences cell-extracellular mat
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21752916?dopt=Abstract
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