Product Name: Phospho-c-Abl (Tyr245) Antibody#2861
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 328232-95-7
Product: MK-0557
Specificity Sensitivity: Phospho-c-Abl (Tyr245) Antibody detects endogenous levels of c-Abl only when phosphorylated at tyrosine 245. The antibody cross-reacts with activated EGF receptors and PDGF receptors.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr245 of human c-Abl.
Background: The c-Abl proto-oncogene encodes a nonreceptor protein tyrosine kinase that is ubiquitously expressed and highly conserved in metazoan evolution. c-Abl protein is distributed in both the nucleus and the cytoplasm of cells. It is implicated in regulating c
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23675446?dopt=Abstract
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