Product Name: MDR1/ABCB1 (D3H1Q) Rabbit mAb#12683
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1904611-63-7
Product: PDE1-IN-2
Specificity Sensitivity: MDR1/ABCB1 (D3H1Q) Rabbit mAb recognizes endogenous levels of total MDR1 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MDR1 protein.
Background: MDR1/ABCB1 belongs to the Mdr/Tap subfamily of the ATP-binding cassette transporter superfamily (1). Multidrug resistance 1 (MDR1) serves as an efflux pump for xenobiotic compounds with broad substrate specificity. MDR1 substrates include therapeutic agen
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20462449?dopt=Abstract
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