Product Name: Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb#6209
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 817194-38-0
Product: GSK180736A
Specificity Sensitivity: Phospho-53BP1 (Ser1618) (D4H11) Rabbit mAb recognizes endogenous levels of 53BP1 protein only when phosphorylated at Ser1618.
Species Reactivity: Human, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser1618 of human 53BP1 protein.
Background: p53-binding protein 1 (53BP1) was originally identified as a p53 binding partner that could enhance the transcriptional activity of p53 (1,2). 53BP1 consists of two BRCA1 carboxy terminal (BRCT) domains that allow for binding to p53 and a separate domain
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24948803?dopt=Abstract
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