Product Name: 14-3-3 γ (D15B7) Rabbit mAb#5522
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 119-04-0
Product: Framycetin
Specificity Sensitivity: 14-3-3γ (D15B7) Rabbit mAb recognizes endogenous levels of total 14-3-3 γ protein. This antibody does not cross-react with other mammalian 14-3-3 isoforms and is predicted to detect 14-3-3γ orthologs in other species, including frog and fish.
Species Reactivity: Human, Mouse, Rat, Monkey, Pig
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ile79 of human 14-3-3 γ protein.
Background: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways (1,2). 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20052282?dopt=Abstract
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