Product Name: Phospho-(Ser) 14-3-3 Binding Motif (4E2) Mouse mAb#9606
Application: Dilutions
Western Blotting: 1:4000
Immunoprecipitation: 1:20
Immunohistochemistry:
Peptide ELISA: 1:1000
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 192705-79-6
Product: PD-166866
Specificity Sensitivity: Phospho-(Ser) 14-3-3 Binding Motif (4E2) Mouse mAb binds peptides and proteins containing phospho-Ser surrounded by Pro at the +2 position and Arg/Lys at the -3 position. By ELISA, the antibody recognizes a wide range of peptides containing this phosphory
Species Reactivity: Human, All Species Expected
Source Purification: Monoclonal antibody is produced by immunizing animals with phospho-(Ser) 14-3-3 binding motif peptides .
Background: The 14-3-3 proteins are a highly conserved family of proteins involved in the regulation of cell survival, apoptosis, proliferation and checkpoint control (1-5). Biological regulation by 14-3-3 is mediated through phosphorylation-dependent protein-protein
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25016019?dopt=Abstract
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