Product Name :
Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488)
Applications:
ICC/IF,Flow Cyt
Reactivity :
Alpaca IgG2b(Fcγ Fragment specific)
Conjugate:
iFluor488
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488) is designed for detecting Alpaca IgG2b specifically. Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488) is based on monoclonal, recombinant, rabbit IgG Fc fused single domain antibody to Alpaca IgG2b(Fcγ Fragment specific) coupled to iFluor488, and Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488) reacts with Alpaca IgG2b selectively, no cross-reactivity with Alpaca IgG1/2c. | Immunogen: Recombinant Fc region of alpaca IgG2b | Host: Camel | Isotype: VHH domain of camel IgG3 fused to rabbit IgG Fc(mutation) | Conjugate: iFluor488 (Ex=495nm, Em=519nm), 3 moles iFluor488 per mole IgG | Specificity: Alpaca IgG2b(Fcγ Fragment specific) | Cross-Reactivity: No cross-reactivity with Alpaca IgG1/2c | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C(Avoid freeze / thaw cycles), Protect from light | Background:The biological family Camelidae comprises camels (one-humped Camelus dromedarius and two-humped Camelus bactrianus), llama (Lama glama and Lama guanicoe), and vicugna (Vicugna vicugna and Vicugna pacos).{{1809336-39-7} MedChemExpress|{1809336-39-7} Biological Activity|{1809336-39-7} Data Sheet|{1809336-39-7} manufacturer} Camelidae contain two kinds of IgG in serum: conventional antibodies (IgG1) containing two light chains and two heavy chains (composed of the VH, CH1, hinge, and CH2 and CH3 domains) and two types of homodimeric heavy-chain antibodies (HCAbs), IgG2 and IgG3, which comprise only H chains; each H chain contains a VHH, hinge, and CH2 and CH3 domains.{{112648-68-7} medchemexpress|{112648-68-7} Technical Information|{112648-68-7} Description|{112648-68-7} supplier} The smallest intact functional antigen-binding fragment of HCAbs is the single-domain VHH, also known as a nanobody(Nb).PMID:20301318 Alpaca is also called Vicugna pacos. Alpaca IgG contains IgG1a, IgG1b, IgG2b, IgG2c and IgG3.
Description2 :
Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488) is designed for detecting Alpaca IgG2b specifically. Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488) is based on monoclonal, recombinant, rabbit IgG Fc fused single domain antibody to Alpaca IgG2b(Fcγ Fragment specific) coupled to iFluor488, and Anti-Alpaca IgG2b(Fcγ Fragment specific), Rabbit antibody(iFluor488) reacts with Alpaca IgG2b selectively, no cross-reactivity with Alpaca IgG1/2c.
Immunogen:
Recombinant Fc region of alpaca IgG2b
Host :
Camel
Isotype:
VHH domain of camel IgG3 fused to rabbit IgG Fc(mutation)
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C(Avoid freeze / thaw cycles), Protect from light
Function:
ICC/IF: 1:100-1:1000FCM: 1:100-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc. The actual dilution used must be determined empirically.
