Product Name :
Tirabrutinib
Description:
Tirabrutinib (ONO-4059) is a selective and novel inhibitor of BTK with IC50 2.2 nM, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.
CAS:
1351636-18-4
Molecular Weight:
454.48
Formula:
C25H22N6O3
Chemical Name:
6-amino-9-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-7-(4-phenoxyphenyl)-8,9-dihydro-7H-purin-8-one
Smiles :
CC#CC(=O)N1C[C@@H](CC1)N1C(=O)N(C2C1=NC=NC=2N)C1C=CC(=CC=1)OC1C=CC=CC=1
InChiKey:
SEJLPXCPMNSRAM-GOSISDBHSA-N
InChi :
InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Hyaluronic acid} MedChemExpress|{Hyaluronic acid} Endogenous Metabolite|{Hyaluronic acid} Biological Activity|{Hyaluronic acid} References|{Hyaluronic acid} custom synthesis|{Hyaluronic acid} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tirabrutinib (ONO-4059) is a selective and novel inhibitor of BTK with IC50 2.2 nM, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.{{Tedizolid} site|{Tedizolid} Anti-infection|{Tedizolid} Biological Activity|{Tedizolid} Purity|{Tedizolid} supplier|{Tedizolid} Epigenetics} |Product information|CAS Number: 1351636-18-4|Molecular Weight: 454.PMID:24257686 48|Formula: C25H22N6O3|Chemical Name: 6-amino-9-[(3R)-1-(but-2-ynoyl)pyrrolidin-3-yl]-7-(4-phenoxyphenyl)-8,9-dihydro-7H-purin-8-one|Smiles: CC#CC(=O)N1C[C@@H](CC1)N1C(=O)N(C2C1=NC=NC=2N)C1C=CC(=CC=1)OC1C=CC=CC=1|InChiKey: SEJLPXCPMNSRAM-GOSISDBHSA-N|InChi: InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 100 mg/mL (220.03 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
