Product Name :
PP1
Description:
PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. PP1 effectively blocks TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells. PP1 blocks TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors. PP1 was also found to potentiate tumor-suppressive effect of connexin 32 gene in renal cancer cells.
CAS:
172889-26-8
Molecular Weight:
281.36
Formula:
C16H19N5
Chemical Name:
1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Smiles :
CC1C=CC(=CC=1)C1=NN(C2=NC=NC(N)=C12)C(C)(C)C
InChiKey:
ZVPDNRVYHLRXLX-UHFFFAOYSA-N
InChi :
InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PP1 is a potent and selective Src family protein tyrosine kinase inhibitor. PP1 effectively blocks TGF-beta1-induced cell migration and invasion in both established and primary carcinoma cells. PP1 blocks TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors. PP1 was also found to potentiate tumor-suppressive effect of connexin 32 gene in renal cancer cells.|Product information|CAS Number: 172889-26-8|Molecular Weight: 281.36|Formula: C16H19N5|Chemical Name: 1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine|Smiles: CC1C=CC(=CC=1)C1=NN(C2=NC=NC(N)=C12)C(C)(C)C|InChiKey: ZVPDNRVYHLRXLX-UHFFFAOYSA-N|InChi: InChI=1S/C16H19N5/c1-10-5-7-11(8-6-10)13-12-14(17)18-9-19-15(12)21(20-13)16(2,3)4/h5-9H,1-4H3,(H2,17,18,19)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ambrisentan} medchemexpress|{Ambrisentan} GPCR/G Protein|{Ambrisentan} Protocol|{Ambrisentan} In Vitro|{Ambrisentan} custom synthesis|{Ambrisentan} Cancer} |Shelf Life: ≥360 days if stored properly.{{Norfluoxetine} site|{Norfluoxetine} GPCR/G Protein|{Norfluoxetine} NF-κB|{Norfluoxetine} Biological Activity|{Norfluoxetine} In Vivo|{Norfluoxetine} custom synthesis} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24238415 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
