f ladies 57 (1,955). Most frequent predisposing things had been immobility (45 ), active

f ladies 57 (1,955). Most frequent predisposing things had been immobility (45 ), active cancer (35 ), recent surgery (33 ) Onefourth of PE had a Pulmonary Embolism IL-6 Antagonist Synonyms Severity Index (PESI) with 0 points. A lot more than 91.7 received some sort of therapy: 86 lowmolecular-weight heparin, of which 33 had been prescribed in mixture having a vitamin K antagonist since the starting. Recurrence, key bleeding and mortality rates inside 30 days had been 10 , five and 14 Caspase 10 Activator drug respectively., obesity (26 ), current hospitalization (22 ) and earlier VTE (21 ). Conclusions: A higher proportion of VTE demands hospitalization for their management, even PE with low sPESI. Mortality and complication remain elevated. We encourage the improvement and maintenance of much more VTE registries in Latin America, to totally comprehend the neighborhood characteristics of this disease. PB1211|Variations of Profile and Management of Cancerassociated Thrombosis inside a RIETE’s Hospital in Brazil J. de Abreu Couto Vieira; R. Santos de Oliveira J ior; A.T. Cavalcanti Rocha Escola Bahiana de Medicina e Sa e P lica, Salvador, Brazil Background: Clinical management and therapy of cancerassociated thrombosis (CAT) are crucial challenges for physicians that take care of venous thromboembolism (VTE). FIGURE two VTE: characteristics of hospitalization and initial therapy management FIGURE 1 VTE episodes among 2006 andABSTRACT889 of|Aims: To evaluate the profile and management of patients with CAT in a private hospital in Salvador, participating in the RIETE registry. Strategies: Consecutive individuals from 5/2018 to 12/2019 have been evaluated and differences between CAT patients and other-VTE individuals had been compared. Benefits: From the 95 individuals, 67.4 had been ladies, the mean age 53.29 years (18.99) and, larger for CAT, 65.82 (five.63) than for otherVTE, 49.52 (eight.36), P 0.001). There have been 64.two PE, 17.9 DVT/ PE and 17.9 DVT, with higher rates of PE amongst CAT and otherVTE and there was no incidental PE. The main cancer web site was breast 27.3 , prostate 18.two and lung 13.six . Amongst the threat elements for CAT, 13.six employed hormones, 18.2 history of VTE, 22.7 TABLE 1 Anticoagulation Therapy for Upkeep immediately after DischargeTotal Variables Anticoagulant of maintenance Enoxaparin Warfarin Rivaroxaban Apixaban Edoxaban Total three (three.9) 25 (19.5) 36 (46.8) 20 (26.0) three (three.9) 95 (one hundred) 2 (three.3) 14 (23.3) 29 (48.three) 13 (21.7) two (three.three) 73 (76.eight) N ( ) No cancer N ( )had obesity, 13.6 immobility four days, 9.1 smoking, four.five recent travel6 hours, none had family history of VTE; hypertension was a lot more frequent in CAT than other-VTE: 63.six vs. 39.7 , P = 0.05. The mean length-of-stay was 9,13.99 days, being shorter for CAT (7.77.52 days). The initial choice of anticoagulant for all cancer individuals was enoxaparin one hundred ; the decision for maintenance therapy following discharge for this group was rivaroxaban 41.2 and apixaban 41.two . There have been some differences in between the decision of anticoagulants for CAT as well as other VTE, nonetheless, each enoxaparin and rivaroxaban had been by far the most used in both groups and in both situations, respectively.Cancer N ( ) P-value1 (five.9) 1 (five.9) 7 (41.two) 7 (41.two) 1 (five.9) 22 (23.two)0.-TABLE 2 Primary Cancer Websites among Individuals with Diagnosis of Thromboembolism (VTE)Key web-site of cancer Breast Prostate Lung Colorectal Kidney Pancreas Hematological Other people Total = 22 n ( ) 6 (27.3) 4 (18.2) 3 (13.6) 2 (9.1) two (9.1) 2 (9.1) two (9.1) 1 (four.5)PB1212|Trombophilia as well as other Danger Elements of Cerebral Venous Sinus Thrombosis in 255 Individuals A. Gwoz