Product Name :
Rabbit anti-XPO1 Polyclonal Antibody
Synonym :
CRM1; emb; exp1
Host :
Rabbit
Species Reactivity:
Human, Mouse
Specificity :
Predicted Reactivity:
Applications :
WB 1:500 – 1:2000
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1000 to the C-terminus of human XPO1 (NP_003391.1).
Concentration :
Purification :
Affinity purification
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20 ℃Avoid freeze / that cycles
Research areas :
Background :
This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
UniProt :
O14980
Additional information:
Product Details FAQ Citations(2) Video Pictures Documents |Overview |Synonym CRM1; emb; exp1 |Host Rabbit |Species Reactivity Human, Mouse |Applications WB 1:500 – 1:2000 |Immunogen A synthetic peptide corresponding to a sequence within amino acids 1000 to the C-terminus of human XPO1 (NP_003391.1). |Positive control U-87MG,B-cell,Mouse liver |Properties |Purification Affinity purification |Clonality Polyclonal Antibody |Isotype IgG |Storage Temp. Store at -20 ℃Avoid freeze / that cycles |Storage Buffer Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |Target |Background This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. |Cellular localization Cajal body,Cytoplasm,Nucleus,nucleolus,nucleoplasm |UniProt O14980 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-XPO1 Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
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