Product Name :
BMf-BH3
Description:
BMf-BH3 belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death.
CAS:
Molecular Weight:
3012.45
Formula:
C131H215N45O35S
Chemical Name:
BMf-BH3
Smiles :
C[C@@H](O)[C@H](NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(O)=O
InChiKey:
BVLSNQUOXXVSOM-KFHPHGKKSA-N
InChi :
InChI=1S/C131H215N45O35S/c1-17-66(11)101(174-116(198)84(36-41-97(137)181)164-125(207)100(65(9)10)173-115(197)85(37-42-98(182)183)157-104(186)68(13)153-108(190)78(30-24-44-147-129(138)139)160-120(202)89(51-73-55-144-59-150-73)169-112(194)81(33-38-94(134)178)158-107(189)76(133)47-62(3)4)126(208)154-69(14)105(187)156-79(31-25-45-148-130(140)141)109(191)159-77(29-22-23-43-132)110(192)166-86(48-63(5)6)117(199)162-83(35-40-96(136)180)114(196)172-93(58-212)124(206)175-102(67(12)18-2)127(209)155-70(15)106(188)165-92(54-99(184)185)122(204)163-82(34-39-95(135)179)113(195)168-88(50-72-27-20-19-21-28-72)119(201)170-90(52-74-56-145-60-151-74)121(203)161-80(32-26-46-149-131(142)143)111(193)167-87(49-64(7)8)118(200)171-91(53-75-57-146-61-152-75)123(205)176-103(71(16)177)128(210)211/h19-21,27-28,55-57,59-71,76-93,100-103,177,212H,17-18,22-26,29-54,58,132-133H2,1-16H3,(H2,134,178)(H2,135,179)(H2,136,180)(H2,137,181)(H,144,150)(H,145,151)(H,146,152)(H,153,190)(H,154,208)(H,155,209)(H,156,187)(H,157,186)(H,158,189)(H,159,191)(H,160,202)(H,161,203)(H,162,199)(H,163,204)(H,164,207)(H,165,188)(H,166,192)(H,167,193)(H,168,195)(H,169,194)(H,170,201)(H,171,200)(H,172,196)(H,173,197)(H,174,198)(H,175,206)(H,176,205)(H,182,183)(H,184,185)(H,210,211)(H4,138,139,147)(H4,140,141,148)(H4,142,143,149)/t66-,67-,68-,69-,70-,71+,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,100-,101-,102-,103-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.XE991 custom synthesis
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
BMf-BH3 belongs to the Bcl-2 apoptosis mediator family. BH3-only protein, Bmf is a key molecule for histone deacetylase (HDAC) inhibitors mediated enhancing effect on ionizing radiation-induced cell death.|Product information|Molecular Weight: 3012.45|Formula: C131H215N45O35S|Chemical Name: BMf-BH3|Smiles: C[C@@H](O)[C@H](NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(O)=O|InChiKey: BVLSNQUOXXVSOM-KFHPHGKKSA-N|InChi: InChI=1S/C131H215N45O35S/c1-17-66(11)101(174-116(198)84(36-41-97(137)181)164-125(207)100(65(9)10)173-115(197)85(37-42-98(182)183)157-104(186)68(13)153-108(190)78(30-24-44-147-129(138)139)160-120(202)89(51-73-55-144-59-150-73)169-112(194)81(33-38-94(134)178)158-107(189)76(133)47-62(3)4)126(208)154-69(14)105(187)156-79(31-25-45-148-130(140)141)109(191)159-77(29-22-23-43-132)110(192)166-86(48-63(5)6)117(199)162-83(35-40-96(136)180)114(196)172-93(58-212)124(206)175-102(67(12)18-2)127(209)155-70(15)106(188)165-92(54-99(184)185)122(204)163-82(34-39-95(135)179)113(195)168-88(50-72-27-20-19-21-28-72)119(201)170-90(52-74-56-145-60-151-74)121(203)161-80(32-26-46-149-131(142)143)111(193)167-87(49-64(7)8)118(200)171-91(53-75-57-146-61-152-75)123(205)176-103(71(16)177)128(210)211/h19-21,27-28,55-57,59-71,76-93,100-103,177,212H,17-18,22-26,29-54,58,132-133H2,1-16H3,(H2,134,178)(H2,135,179)(H2,136,180)(H2,137,181)(H,144,150)(H,145,151)(H,146,152)(H,153,190)(H,154,208)(H,155,209)(H,156,187)(H,157,186)(H,158,189)(H,159,191)(H,160,202)(H,161,203)(H,162,199)(H,163,204)(H,164,207)(H,165,188)(H,166,192)(H,167,193)(H,168,195)(H,169,194)(H,170,201)(H,171,200)(H,172,196)(H,173,197)(H,174,198)(H,175,206)(H,176,205)(H,182,183)(H,184,185)(H,210,211)(H4,138,139,147)(H4,140,141,148)(H4,142,143,149)/t66-,67-,68-,69-,70-,71+,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,100-,101-,102-,103-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Ketodarolutamide Activator |Shelf Life: ≥12 months if stored properly.PMID:32791892 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
