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Product Name :
Talniflumate

Description:
Talniflumate (BA 7602-06) is the prodrug of Niflumic acid (HY-B0493), exerting its activity in the body through conversion to niflumic acid by esterase. Talniflumate is an orally active Ca2+-activated Cl- channel (CaCC) blocker. Talniflumate can be used as an analgesic and anti-inflammatory agent in cystic fibrosis mouse model of distal intestinal obstructive syndrome.

CAS:
66898-62-2

Molecular Weight:
414.33

Formula:
C21H13F3N2O4

Chemical Name:
3-oxo-1,3-dihydro-2-benzofuran-1-yl 2-[3-(trifluoromethyl)phenyl]aminopyridine-3-carboxylate

Smiles :
O=C(OC1OC(=O)C2C=CC=CC=21)C1=CC=CN=C1NC1C=C(C=CC=1)C(F)(F)F

InChiKey:
ANMLJLFWUCQGKZ-UHFFFAOYSA-N

InChi :
InChI=1S/C21H13F3N2O4/c22-21(23,24)12-5-3-6-13(11-12)26-17-16(9-4-10-25-17)19(28)30-20-15-8-2-1-7-14(15)18(27)29-20/h1-11,20H,(H,25,26)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Tiamulin Epigenetics

Shelf Life:
≥12 months if stored properly.Remogliflozin etabonate Purity

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Talniflumate (BA 7602-06) is the prodrug of Niflumic acid (HY-B0493), exerting its activity in the body through conversion to niflumic acid by esterase. Talniflumate is an orally active Ca2+-activated Cl- channel (CaCC) blocker. Talniflumate can be used as an analgesic and anti-inflammatory agent in cystic fibrosis mouse model of distal intestinal obstructive syndrome.|Product information|CAS Number: 66898-62-2|Molecular Weight: 414.33|Formula: C21H13F3N2O4|Chemical Name: 3-oxo-1,3-dihydro-2-benzofuran-1-yl 2-[3-(trifluoromethyl)phenyl]aminopyridine-3-carboxylate|Smiles: O=C(OC1OC(=O)C2C=CC=CC=21)C1=CC=CN=C1NC1C=C(C=CC=1)C(F)(F)F|InChiKey: ANMLJLFWUCQGKZ-UHFFFAOYSA-N|InChi: InChI=1S/C21H13F3N2O4/c22-21(23,24)12-5-3-6-13(11-12)26-17-16(9-4-10-25-17)19(28)30-20-15-8-2-1-7-14(15)18(27)29-20/h1-11,20H,(H,25,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 83.PMID:33085358 33 mg/mL (201.12 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Talniflumate (oral chow; 0.4 mg/g; 21 days) significantly increases CF mouse survival from 26 to 77%. It does not alter crypt goblet cell numbers or change intestinal expression of mCLCA3 but tends to decrease crypt mucoid impaction.|Products are for research use only. Not for human use.|

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Author: Interleukin Related