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Product Name :
Roflumilast Impurity E

Description:
Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.

CAS:
1391052-76-8

Molecular Weight:
349.12

Formula:
C13H8Cl2F2N2O3

Chemical Name:
N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-hydroxybenzamide

Smiles :
OC1=CC(=CC=C1OC(F)F)C(=O)NC1C(Cl)=CN=CC=1Cl

InChiKey:
GZHTYXYJBZYTEV-UHFFFAOYSA-N

InChi :
InChI=1S/C13H8Cl2F2N2O3/c14-7-4-18-5-8(15)11(7)19-12(21)6-1-2-10(9(20)3-6)22-13(16)17/h1-5,13,20H,(H,18,19,21)

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Macitentan} web|{Macitentan} Apoptosis|{Macitentan} Technical Information|{Macitentan} Data Sheet|{Macitentan} custom synthesis|{Macitentan} Autophagy}

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.|Product information|CAS Number: 1391052-76-8|Molecular Weight: 349.12|Formula: C13H8Cl2F2N2O3|Chemical Name: N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)-3-hydroxybenzamide|Smiles: OC1=CC(=CC=C1OC(F)F)C(=O)NC1C(Cl)=CN=CC=1Cl|InChiKey: GZHTYXYJBZYTEV-UHFFFAOYSA-N|InChi: InChI=1S/C13H8Cl2F2N2O3/c14-7-4-18-5-8(15)11(7)19-12(21)6-1-2-10(9(20)3-6)22-13(16)17/h1-5,13,20H,(H,18,19,21)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Selinexor} web|{Selinexor} Membrane Transporter/Ion Channel|{Selinexor} Protocol|{Selinexor} In stock|{Selinexor} custom synthesis|{Selinexor} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.PMID:24220671 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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