Product Name :
MCL-1/BCL-2-IN-3
Description:
MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively.
CAS:
2163793-55-1
Molecular Weight:
569.47
Formula:
C27H25BrN2O5S
Chemical Name:
methyl 5-[(2-{8-[(4-bromophenyl)sulfanyl]-2,4-dioxo-3-azatricyclo[7.3.1.0⁵,¹³]trideca-1(13),5,7,9,11-pentaen-3-yl}ethyl)carbamoyl]pentanoate
Smiles :
COC(=O)CCCCC(=O)NCCN1C(=O)C2C=CC=C3C=2C(=CC=C3SC2C=CC(Br)=CC=2)C1=O
InChiKey:
HZZXWFWVQWMGAR-UHFFFAOYSA-N
InChi :
InChI=1S/C27H25BrN2O5S/c1-35-24(32)8-3-2-7-23(31)29-15-16-30-26(33)20-6-4-5-19-22(14-13-21(25(19)20)27(30)34)36-18-11-9-17(28)10-12-18/h4-6,9-14H,2-3,7-8,15-16H2,1H3,(H,29,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively.|Product information|CAS Number: 2163793-55-1|Molecular Weight: 569.47|Formula: C27H25BrN2O5S|Chemical Name: methyl 5-[(2-{8-[(4-bromophenyl)sulfanyl]-2,4-dioxo-3-azatricyclo[7.3.1.0⁵,¹³]trideca-1(13),5,7,9,11-pentaen-3-yl}ethyl)carbamoyl]pentanoate|Smiles: COC(=O)CCCCC(=O)NCCN1C(=O)C2C=CC=C3C=2C(=CC=C3SC2C=CC(Br)=CC=2)C1=O|InChiKey: HZZXWFWVQWMGAR-UHFFFAOYSA-N|InChi: InChI=1S/C27H25BrN2O5S/c1-35-24(32)8-3-2-7-23(31)29-15-16-30-26(33)20-6-4-5-19-22(14-13-21(25(19)20)27(30)34)36-18-11-9-17(28)10-12-18/h4-6,9-14H,2-3,7-8,15-16H2,1H3,(H,29,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 17.{{Nordihydroguaiaretic acid} site|{Nordihydroguaiaretic acid} Autophagy|{Nordihydroguaiaretic acid} Protocol|{Nordihydroguaiaretic acid} Description|{Nordihydroguaiaretic acid} manufacturer|{Nordihydroguaiaretic acid} Cancer} 86 mg/mL (31.{{Atezolizumab} site|{Atezolizumab} Autophagy|{Atezolizumab} Purity & Documentation|{Atezolizumab} In stock|{Atezolizumab} supplier|{Atezolizumab} Autophagy} 36 mM; Need ultrasonic).PMID:23600560 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
