Product Name :
Plantanone B
Description:
Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research.
CAS:
55780-30-8
Molecular Weight:
756.66
Formula:
C33H40O20
Chemical Name:
3-(((2S, 3R, 4S, 5S, 6R)-4, 5-dihydroxy-6-((((2R, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3-(((2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5, 7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Smiles :
C[C@@H]1O[C@@H](O[C@H]2[C@H](OC3C(=O)C4=C(C=C(O)C=C4O)OC=3C3C=CC(O)=CC=3)O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
InChiKey:
PSVKHLFIIZQISP-CFRIXVKNSA-N
InChi :
InChI=1S/C33H40O20/c1-10-19(38)23(42)27(46)32(48-10)53-30-25(44)21(40)17(9-47-31-26(45)24(43)20(39)16(8-34)50-31)51-33(30)52-29-22(41)18-14(37)6-13(36)7-15(18)49-28(29)11-2-4-12(35)5-3-11/h2-7,10,16-17,19-21,23-27,30-40,42-46H,8-9H2,1H3/t10-,16+,17+,19-,20+,21+,23+,24-,25-,26+,27+,30+,31+,32-,33-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research.|Product information|CAS Number: 55780-30-8|Molecular Weight: 756.66|Formula: C33H40O20|Chemical Name: 3-(((2S, 3R, 4S, 5S, 6R)-4, 5-dihydroxy-6-((((2R, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3-(((2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5, 7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one|Smiles: C[C@@H]1O[C@@H](O[C@H]2[C@H](OC3C(=O)C4=C(C=C(O)C=C4O)OC=3C3C=CC(O)=CC=3)O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O|InChiKey: PSVKHLFIIZQISP-CFRIXVKNSA-N|InChi: InChI=1S/C33H40O20/c1-10-19(38)23(42)27(46)32(48-10)53-30-25(44)21(40)17(9-47-31-26(45)24(43)20(39)16(8-34)50-31)51-33(30)52-29-22(41)18-14(37)6-13(36)7-15(18)49-28(29)11-2-4-12(35)5-3-11/h2-7,10,16-17,19-21,23-27,30-40,42-46H,8-9H2,1H3/t10-,16+,17+,19-,20+,21+,23+,24-,25-,26+,27+,30+,31+,32-,33-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Vibostolimab} medchemexpress|{Vibostolimab} Purity & Documentation|{Vibostolimab} Purity|{Vibostolimab} manufacturer|{Vibostolimab} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Naptumomab} site|{Naptumomab} Technical Information|{Naptumomab} Data Sheet|{Naptumomab} manufacturer|{Naptumomab} Cancer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23618405 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM. Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively. .Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively.|Products are for research use only. Not for human use.|
