Product Name :
GW791343 trihydrochloride
Description:
GW791343 is a P2X7 allosteric modulator. GW791343 exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 – 7.2) and a positive allosteric modulator of rat P2X7.
CAS:
309712-55-8
Molecular Weight:
483.81
Formula:
C20H27Cl3F2N4O
Chemical Name:
2-[(3,4-difluorophenyl)amino]-N-{2-methyl-5-[(piperazin-1-yl)methyl]phenyl}acetamide trihydrochloride
Smiles :
Cl.Cl.Cl.CC1=CC=C(CN2CCNCC2)C=C1NC(=O)CNC1C=C(F)C(F)=CC=1
InChiKey:
WSBRAHWNJBXXJM-UHFFFAOYSA-N
InChi :
InChI=1S/C20H24F2N4O.3ClH/c1-14-2-3-15(13-26-8-6-23-7-9-26)10-19(14)25-20(27)12-24-16-4-5-17(21)18(22)11-16;;;/h2-5,10-11,23-24H,6-9,12-13H2,1H3,(H,25,27);3*1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bradykinin} site|{Bradykinin} Ser/Thr Protease|{Bradykinin} Purity & Documentation|{Bradykinin} Data Sheet|{Bradykinin} supplier|{Bradykinin} Cancer}
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GW791343 is a P2X7 allosteric modulator. GW791343 exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 – 7.2) and a positive allosteric modulator of rat P2X7.|Product information|CAS Number: 309712-55-8|Molecular Weight: 483.{{S-Adenosyl-L-methionine} web|{S-Adenosyl-L-methionine} Apoptosis|{S-Adenosyl-L-methionine} Technical Information|{S-Adenosyl-L-methionine} In Vitro|{S-Adenosyl-L-methionine} custom synthesis|{S-Adenosyl-L-methionine} Autophagy} 81|Formula: C20H27Cl3F2N4O|Chemical Name: 2-[(3,4-difluorophenyl)amino]-N-{2-methyl-5-[(piperazin-1-yl)methyl]phenyl}acetamide trihydrochloride|Smiles: Cl.PMID:23937941 Cl.Cl.CC1=CC=C(CN2CCNCC2)C=C1NC(=O)CNC1C=C(F)C(F)=CC=1|InChiKey: WSBRAHWNJBXXJM-UHFFFAOYSA-N|InChi: InChI=1S/C20H24F2N4O.3ClH/c1-14-2-3-15(13-26-8-6-23-7-9-26)10-19(14)25-20(27)12-24-16-4-5-17(21)18(22)11-16;;;/h2-5,10-11,23-24H,6-9,12-13H2,1H3,(H,25,27);3*1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
