Product Name :
ITK/TRKA-IN-1
Description:
ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively.
CAS:
2655557-54-1
Molecular Weight:
484.54
Formula:
C25H30F2N6O2
Chemical Name:
(2S)-N-{2-[(4aS, 5aR)-5, 5-difluoro-5a-methyl-1H, 4H, 4aH, 5H, 5aH, 6H-cyclopropa[f]indazol-3-yl]-6-methyl-1H-1, 3-benzodiazol-5-yl}-N-methyl-2-(morpholin-4-yl)propanamide
Smiles :
C[C@@]12CC3NN=C(C4NC5=CC(C)=C(C=C5N=4)N(C)C(=O)[C@H](C)N4CCOCC4)C=3C[C@@H]1C2(F)F
InChiKey:
PWTZWYZDFORBCV-OSZRXVRWSA-N
InChi :
InChI=1S/C25H30F2N6O2/c1-13-9-16-17(11-19(13)32(4)23(34)14(2)33-5-7-35-8-6-33)29-22(28-16)21-15-10-20-24(3,25(20,26)27)12-18(15)30-31-21/h9,11,14,20H,5-8,10,12H2,1-4H3,(H,28,29)(H,30,31)/t14-,20-,24+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Betamethasone valerate} MedChemExpress|{Betamethasone valerate} Vitamin D Related/Nuclear Receptor|{Betamethasone valerate} Protocol|{Betamethasone valerate} References|{Betamethasone valerate} custom synthesis|{Betamethasone valerate} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
ITK/TRKA-IN-1 is a dual inhibitor of IL-2-inducible T-cell kinase (ITK) and tropomyosin receptor kinase A (TRKA) with an IC50 value of 1.0 nM and 96 % inhibition, respectively.|Product information|CAS Number: 2655557-54-1|Molecular Weight: 484.54|Formula: C25H30F2N6O2|Chemical Name: (2S)-N-{2-[(4aS, 5aR)-5, 5-difluoro-5a-methyl-1H, 4H, 4aH, 5H, 5aH, 6H-cyclopropa[f]indazol-3-yl]-6-methyl-1H-1, 3-benzodiazol-5-yl}-N-methyl-2-(morpholin-4-yl)propanamide|Smiles: C[C@@]12CC3NN=C(C4NC5=CC(C)=C(C=C5N=4)N(C)C(=O)[C@H](C)N4CCOCC4)C=3C[C@@H]1C2(F)F|InChiKey: PWTZWYZDFORBCV-OSZRXVRWSA-N|InChi: InChI=1S/C25H30F2N6O2/c1-13-9-16-17(11-19(13)32(4)23(34)14(2)33-5-7-35-8-6-33)29-22(28-16)21-15-10-20-24(3,25(20,26)27)12-18(15)30-31-21/h9,11,14,20H,5-8,10,12H2,1-4H3,(H,28,29)(H,30,31)/t14-,20-,24+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Rilonacept} web|{Rilonacept} Interleukin Related|{Rilonacept} Technical Information|{Rilonacept} Purity|{Rilonacept} manufacturer|{Rilonacept} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:23415682 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Bagley SW, et al. Benzimidazole Derivatives. WO2021124155A1.Products are for research use only. Not for human use.|
