Product Name :
3-Bromocyclohexene, 95%
Synonym:
IUPAC Name :
3-bromocyclohex-1-ene
CAS NO.:
1521-51-3
Molecular Weight :
Molecular formula:
C6H9Br
Smiles:
BrC1CCCC=C1
Description:
In peptide synthesis, can be used to protect the hydroxyl group of serine and threonine as the cyclohexyl (Chx) ether, by reaction with the sodium alkoxide (generated with NaH), followed by hydrogenation. The group is stable to TFA and 20% piperidine in DMF, but can be cleaved with TfOH in TFA, in the presence of thioanisole as a cation scavenger.Epoprostenol sodium It is also used in the synthesis of N-tert-butoxycarbonyl-O-cyclohexyl-L-tyrosine.MS170 1 It was also used in the synthesis of enantiopure cyclohexitols such as muco-quercitol, D-chiro-inocitol and allo-inocitol.PMID:24182988
