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Arsenic compounds are crucial drugs which have been utilised in each People’s Republic of China along with the Western planet for extra than two,000 years. Arsenic trioxide (As2O3) and arsenic sulfide (As4S4) were discovered to possess fantastic anti-leukemic activity in particular against acute promyelocytic leukemia (APL).1? As2O3 has a synergistic impact when combined with all-trans-retinoic acid (ATRA). The exact mechanism of such synergistic impact on APL remains incompletely understood, though it was found that thei.