Product Name: ZO-1 (D7D12) Rabbit mAb#8193
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 483313-22-0
Product: SB-674042
Specificity Sensitivity: ZO-1 (D7D12) Rabbit mAb recognizes endogenous levels of total ZO-1 protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ZO-1 protein.
Background: Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane protein
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24232095?dopt=Abstract
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