Product Name: ZO-1 Antibody#5406
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1206880-66-1
Product: AM679
Specificity Sensitivity: ZO-1 Antibody detects endogenous levels of total ZO-1 protein.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human ZO-1 protein.
Background: Tight junctions, or zona occludens, form a continuous barrier to fluids across the epithelium and endothelium. They function in regulation of paracellular permeability and in the maintenance of cell polarity, blocking the movement of transmembrane protein
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23851309?dopt=Abstract
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