Product Name: Upf1 (D15G6) Rabbit mAb#12040
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1431697-84-5
Product: gamma-secretase modulator 3
Specificity Sensitivity: Upf1 (D15G6) Rabbit mAb recognizes endogenous levels of total Upf1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Upf1 protein.
Background: Upf1 was identified as an active component in nonsense-mediated decay (NMD), an mRNA surveillance mechanism in eukaryotic cells that degrades mRNAs containing premature termination codons (1). Upf1 was found to be an ATP-dependent RNA helicase in the cyto
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22013100?dopt=Abstract
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