Product Name: Upf1 Antibody#9435
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 89565-68-4
Product: Tropisetron
Specificity Sensitivity: Upf1 Antibody detects endogenous levels of total Upf1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Upf1. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Upf1 was identified as an active component in nonsense-mediated decay (NMD), an mRNA surveillance mechanism in eukaryotic cells that degrades mRNAs containing premature termination codons (1). Upf1 was found to be an ATP-dependent RNA helicase in the cyto
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23146905?dopt=Abstract
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