Product Name: Ubc12 Antibody#4913
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 212779-48-1
Product: NG 52
Specificity Sensitivity: Ubc12 Antibody detects endogenous levels of total Ubc12 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding K36 of human Ubc12. Antibodies are purified by peptide affinity chromatography.
Background: Similar to ubiquitin, NEDD8 is covalently linked to target proteins through an enzymatic cascade composed of NEDD8-specific E1 (activating)- and E2 (conjugating)-enzymes (1,2). The E2 ligase specific for NEDD8 is Ubc12 (3-5). Ubc12 forms a heterodimeric c
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23542921?dopt=Abstract
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