Product Name: UBR5 (D6O8Z) Rabbit mAb#65344
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1227678-26-3
Product: CEP-32496 (hydrochloride)
Specificity Sensitivity: UBR5 (D6O8Z) Rabbit mAb recognizes endogenous levels of total UBR5 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human UBR5 protein.
Background: Human E3 identified by differential display (UBR5/EDD) is a HECT domain-containing ubiquitin E3 ligase of the N-end rule pathway that promotes the ubiquitination and proteasomal degradation of proteins harboring N-degrons (1-3). UBR5 represents an ortholo
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24127215?dopt=Abstract
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