Product Name: UBE3A (D10D3) Rabbit mAb#7526
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 114977-28-5
Product: Docetaxel
Specificity Sensitivity: UBE3A (D10D3) Rabbit mAb recognizes endogenous levels of total UBE3A protein. Based upon sequence alignment, this antibody is predicted to cross-react with all UBE3A splice variants.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human UBE3A protein.
Background: UBE3A, also commonly referred to as E6AP (E6 Associated Protein), is an E3 ubiquitin protein ligase and founding member of the HECT (Homologous to the E6 Carboxyl Terminus) family of E3 ligases (1). UBE3A has been shown to be hijacked by the oncogenic E6
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25667444?dopt=Abstract
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