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Product Name: Tyk2 (D4I5T) Rabbit mAb#14193
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 86307-44-0
Product: Impurity C of Calcitriol
Specificity Sensitivity: Tyk2 (D4I5T) Rabbit mAb recognizes endogenous levels of total Tyk2 protein. A band of unknown identity at 55 kDa is detected in some cell lines.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Tyk2 protein.
Background: Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-α and β (1-3). Following ligand binding, Tyk2 is activated by phosphorylat
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18829613?dopt=Abstract

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Author: Interleukin Related