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Product Name: Tyk2 Antibody#9312
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 82266-85-1
Product: Impurity C of Alfacalcidol
Specificity Sensitivity: Tyk2 Antibody detects endogenous levels of total Tyk2 protein. No cross-reactivity was detected with other family members at physiological conditions.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding serine 819 of human Tyk2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-α and β (1-3). Following ligand binding, Tyk2 is activated by phosphorylat
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19188910?dopt=Abstract

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Author: Interleukin Related