Product Name: TrkA and TrkB Antibody Sampler Kit#4638
Application:
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage:
CAS NO.: 1124329-14-1
Product: AZ3146
Specificity Sensitivity: Both total TrkA and TrkB antibodies detect endogenous levels of their respective Trk receptors and do not cross-react with related proteins. The Trk (pan) (A7H6R) Rabbit mAb detects endogenous levels of total TrkA, TrkB, and TrkC proteins. However, the an
Species Reactivity:
Source Purification: Total monoclonal antibodies are produced by immunizing animals with synthetic peptides (KLH-coupled) surrounding Arg220 of human TrkA, Pro50 of human TrkB, and Tyr791 of human TrkA. Activation state monoclonal antibodies are produced by immunizing animals
Background: The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3 (1). Neurotrophi
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20231380?dopt=Abstract
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