Product Name: TTK (D15B7) Rabbit mAb#5469
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 845714-00-3
Product: PHA-767491
Specificity Sensitivity: TTK (D15B7) Rabbit mAb detects endogenous levels of total TTK protein. A background band of unknown origin is detected at 70 kDa.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to a region surrounding Ala560 of human TTK protein.
Background: TTK (Mps1, PYT) is a cell cycle regulated dual specificity kinase present in rapidly proliferating tissues and cell lines (1-3). TTK localizes to kinetochores and centromeres and is an essential component of the mitotic spindle checkpoint as well as centr
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25412842?dopt=Abstract
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