Product Name: TREX1 Antibody#12215
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1186195-60-7
Product: MTEP (hydrochloride)
Specificity Sensitivity: TREX1 Antibody recognizes endogenous levels of total TREX1 protein.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro317 of human TREX1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: TREX1 is a broadly expressed 3’ to 5’ exonuclease that acts on single-stranded DNA (ssDNA) to negatively regulate the interferon-stimulatory DNA (ISD) response (1-4). In humans, there are three TREX1 isoforms generated through alternative splicing with pr
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21181942?dopt=Abstract
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